The median survival of the entire group has not yet been reached. After a mean follow-up of 46.9 months, the overall 5-year Kaplan-Meier survival estimate was 67.7%. Results There were no operative deaths, and all patients left the hospital. A multivariate Cox proportional hazards model was used to determine the effects of various factors on long-term survival after resection. Main Outcome Measures Postoperative survival. Interventions Pylorus-preserving Whipple resection in 32 patients and standard Whipple resection in 23 patients. Patients Fifty-five consecutive patients who underwent Whipple resection for ampullary adenocarcinoma from 1988 through 2001. Setting Major academic medical and pancreatic surgical center. Hypothesis After resection of an adenocarcinoma of the ampulla of Vater, certain clinical and pathologic characteristics influence long-term survival. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.
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